Thermo NanoDrop One with PC and Software

Thermo NanoDrop One with PC and Software – Product Introduction

The Thermo Scientific NanoDrop One is a compact, high-precision microvolume UV-Vis spectrophotometer designed for rapid and accurate quantification of DNA, RNA, protein, and other biomolecules. As one of the most widely used instruments in molecular biology laboratories, the NanoDrop One combines ease of use, minimal sample requirements, and high measurement accuracy, making it an essential tool for life science research, clinical diagnostics, and biotechnology applications.

This configuration includes the original PC workstation and installed software, providing a complete ready-to-use analytical solution. With integrated data acquisition and analysis capabilities, the system ensures seamless operation from measurement to reporting, reducing workflow complexity and improving laboratory efficiency.

The NanoDrop One operates using patented microvolume sample retention technology, which allows users to measure samples without the need for cuvettes or dilution. Only 1–2 µL of sample is required, which is placed directly onto the measurement pedestal. The system automatically forms a liquid column between the upper and lower optical surfaces, enabling precise UV-Vis absorbance readings in seconds.

One of the key advantages of the NanoDrop One is its ability to deliver highly accurate nucleic acid quantification. It measures DNA, RNA, and oligonucleotides across a broad concentration range while also providing purity assessment through A260/A280 and A260/A230 ratios. This allows researchers to quickly evaluate sample quality before downstream applications such as PCR, sequencing, cloning, and gene expression analysis.

The included PC system and NanoDrop software enhance usability by offering intuitive control, real-time spectral visualization, and automated result interpretation. Users can easily switch between measurement modes, store experimental methods, and generate exportable reports. The software also includes built-in contaminant analysis tools that help identify potential impurities such as proteins, phenol, or salts in nucleic acid samples.

The NanoDrop One is equipped with Acclaro Sample Intelligence technology, which improves measurement accuracy by detecting and correcting for sample contaminants. This feature ensures more reliable results, especially in complex biological samples where purity may vary. The system also provides spectral analysis across the full UV-Vis range, enabling researchers to identify unexpected absorbance patterns.

Designed for modern laboratory workflows, the instrument supports fast measurement cycles, typically delivering results in under 5 seconds per sample. Its compact footprint allows it to be placed directly on the benchtop without requiring additional accessories or infrastructure. The rugged optical design ensures long-term stability and consistent performance even under high-throughput conditions.

The inclusion of the original PC workstation ensures full compatibility with Thermo Scientific software updates and data management systems. It enables secure data storage, traceability, and compliance with laboratory quality standards such as GLP. This makes the system suitable not only for academic research but also for regulated environments.

In summary, the Thermo NanoDrop One with PC and Software is a powerful, user-friendly microvolume spectrophotometer that delivers fast, accurate, and reproducible biomolecule quantification. Its combination of minimal sample consumption, advanced optical technology, and integrated software workflow makes it one of the most efficient tools for modern molecular biology laboratories.

Technical Specifications